Vaccine Made in China and SARS2 Mutation in India.

Zhiyan-Le, 2021-04-28.。
Chinese Version:
https://sites.google.com/site/zhiyanleback/2021-1/z20210428-vaccine-india
https://zhiyanleback.blogspot.com/p/vaccine-made-in-china-vaccine-and-sars2.html 


1]: China Vaccine Effective Ratio: 3% for one dose.

The PRC state-run media has claimed that its SARS-2 vaccine is 100% effective with no side effects. Their example is Chile. However, according to WHO, cases in Chile has increased since applying China-made vaccines:



When citing Western news, the PRC media deleted 3% effective ratio. For example:

Chile has one of the world’s best vaccination rates. Covid is surging there anyway.
MON, APR 19 2021 1:28 AM EDT
A study published by the University of Chile earlier this month reported that CoronaVac was 56.5% effective two weeks after the second doses were administered in the country. Crucially, however, they also reported that one dose was only 3% effective.

That may well explain why the cases have increased in Chile after the country applied China-made covid vaccine. However, in the PRC official media, such as the Global Times, the 3% of the effective rate of one dose is cut off, i.e., knowingly used fraud story to mislead the Chinese people and people around the world.


2]: SARS-2 Mutation in India Indicated a qualitative change.

Even if some of the vaccines are now effective, they may fail in a longer hall match. The following is a summary of recent SARS-2 mutations in India:



In the above, BC is the basic codon, I to VI refer to hidden codons of each basic codon. REF and ALT are the codons before and after the mutation, respectively. The numbers are codes re energy level of each codon.

It tells: the mutation in S–gene lost 171 units re energy level and, at the same time, mutations in unctional gene groups gained 250 units. Overall, the mutation in India increased energy level by 79 units.

This mutation well suggested that the SARS-2 development has finished its phase-I, which focused on genetic changes in S-gene re how to fit into human body. Now phase-II is starting, which will focus on function changes in different genetic groups, meaning that the current vaccines need new versions, or they may not work.

This mutation in India also tells that the pandemic origin is in mainland China. Below is global ACE2 changes and frequencies (published by NIH):



It shows that the Far East population (mostly the Chinese in mainland China) has the highest receptor expression frequency, with an average of 0.9805 after mutation; while the average receptor expression frequency of South Asia (most of the population is Indian population) is 0.7545, which is higher than that in Europe and Americas by 10 points but lower than that in China by 23 points.

This well suggests that, before the global epidemic broke out, SARS-2 had already had good fitness with Chinese population in mainland China, meaning that PRC is the original place re SARS-2 where the pandemic had been initialized then started.

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